JSTSP Volume 14 Issue 6

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September, 2020

JSTSP Volume 14 Issue 6

Recently, deep neural network (DNN) based methods for low-dose CT have been investigated to achieve excellent performance in both image quality and computational speed. However, almost all methods using DNNs for low-dose CT require clean ground truth data with full radiation dose to train the DNNs. In this work, we attempt to train DNNs for low-dose CT reconstructions with reduced tube current by investigating unsupervised training of DNNs for denoising sensor measurements or sinograms without full-dose ground truth images.

Regularization by denoising (RED) is an image reconstruction framework that uses an image denoiser as a prior. Recent work has shown the state-of-the-art performance of RED with learned denoisers corresponding to pre-trained convolutional neural nets (CNNs). In this work, we propose to broaden the current denoiser-centric view of RED by considering priors corresponding to networks trained for more general artifact-removal.

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