The Machine Learning for Signal Processing Technical Committee (MLSP TC) is at the interface between theory and application, developing novel theoretically-inspired methodologies targeting both longstanding and emergent signal processing applications. A main TC-sponsored annual event is the IEEE Workshop on Machine Learning for Signal Processing. The Nineteenth MLSP Workshop was successfully held in September 2009 in the city of Grenoble, France, with picturesque views of mountains leading up to the Alps.