Wearable sensor technology has improved substantially in recent years – and the personalized healthcare movement is reaping the benefits. Specifically, advancements in miniaturization, smart materials, low-power consumption and ruggedness have transformed ubiquitous monitoring. Monitoring vital physiological parameters including body temperature, heart rate, blood pressure, sugar level, and oxygen saturation in blood is now standard – and affordable. Today’s increasingly compact, wearable designs incorporate and leverage numerous sensors: accelerometers, SpO2, (an estimate of oxygen saturation in the blood), heart/pulse rate, electrocardiography (ECG), and electroencephalography (EEG), among them. Signal processing plays a significant role too; techniques applied on the acquired sensor data – real-time and off-line – continue to enhance the value, and progress, of healthcare monitoring, which is crucial for use by the public.