SPS BSI Webinar: The Connectome Multiplex
Date: 31 January 2025
Time: 1:00 PM ET (New York Time)
Presenter(s): Dr. Sepideh Sadaghiani
Meeting information:
Meeting number: 2633 738 3332
Password: nJQrHBud326 (65774283 when dialing from a phone or video system)
Join by phone:
+1-415-655-0002 US Toll
Access code: 2633 738 3332
Join us 31 January 2025, at 1:00 PM ET for an exciting virtual talk by Dr. Sepideh Sadaghiani entitled: “The connectome multiplex” as part of the activities of the Brain Space Initiative, co-sponsored by the Center for Translational Research in Neuroimaging and Data Science (TReNDS) and the Data Science Initiative, IEEE Signal Processing Society.
Abstract
The human functional connectome has become synonymous with its fMRI heritage, which yields connectivity on the basis of extremely slow fluctuations of the hemodynamic signal. More recently however, these slow connectivity patterns have been complemented with fast connectivity from electrophysiological measures. In this talk, I will discuss synergistic investigations of the functional connectome that use multiple complimentary acquisition methods. This multi-modal approach has demonstrated that the connectome comprises both fast, oscillation-based connectivity observable in EEG, and extremely slow connectivity best captured with fMRI. While the fast and slow processes share spatial organization, these processes unfold in a temporally independent manner. Our findings suggest that equivalent dynamics are engaged across all timescales, but at different speeds. Infraslow and rapid connectivity of various frequency bands can thus be conceptualized as a multiplex of concurrent trajectories through a shared space of discrete connectome states. In conclusion, basic and translational research will benefit from comprehensively considering the full breadth of the functional connectome’s timescales.
Biography
Sepideh Sadaghiani is Associate Professor of Psychology and Bioengineering, at the University of Illinois, Urbana-Champaign. She directs the CONNECTlab at the Beckman Institute for Advanced Science and Technology where she is full-time faculty. Sadaghiani received her Ph.D. in Neural and Behavioral Sciences from the Max Planck Graduate School and postdoctoral training at Berkeley and Stanford. She investigates the role of neural connectivity and spontaneous brain activity in cognitive control and behavior through a multi-modal lens. Sadaghiani serves as handling editor of Imaging Neuroscience and Network Neuroscience. She has been recognized as National Science Foundation (NSF) CAREER Awardee, and her work has been funded by the National Institutes of Health and the NSF.
Recommended Articles:
- Mostame P, Wirsich J, Alderson TH, Ridley B, Giraud A-L, Carmichael D, Vulliemoz S, Guye M, Lemieux L, Sadaghiani S (2024). A multiplex of dynamic connectome trajectories enables several connectivity patterns in parallel. eLife. (Link to Paper).
- Jun S, Malone SM, Alderson TH, Iacono WG, Harper J, Wilson S, Sadaghiani S (2024) Rapid dynamics of electrophysiological connectome states are heritable. Network Neuroscience. (Link to Paper).
- Jun S, Malone SM, Alderson TH, Iacono WG, Harper J, Wilson S, Sadaghiani S (2024) Cognitive abilities are associated with rapid dynamics of electrophysiological connectome states. Network Neuroscience. (Link to Paper).
- Sadaghiani S, Brookes M, Baillet S. (2022) Connectomics of human electrophysiology. Invited contribution to special issue on Mapping the Connectome. NeuroImage. (Link to Paper).
