Sanjit Mitra and Thanos Stouraitis General Chairs, ISCCSP 2014 Τhe 6th edition of the International Symposium on Communications, Control, and Signal Processing (ISCCSP 2014) was held during 21-24 May 2014, in Athens, Greece. In addition to regular papers, ISCCSP 2014 included six exciting plenary lectures and many special sessions. About 170 participants gathered from 43 countries around the world to present their recent research results and discuss in a wonderful setting. We thank them for submitting their work to ISCCSP. We also thank the many volunteers who worked hard to enhance this unique conference. We would like to express our thanks to our sponsor, the University of Patras, Greece, as well as to our technical co-sponsors, the IEEE Circuits and Systems Society, the IEEE Control Systems Society, and the IEEE Signal Processing Society. The 7th edition of ISCCSP will be held at Dubrovnik, Croatia in May 2016.